Given America's present position of influence in the world, I sometimes wonder whether US foreign policy* has a more significant cumulative effect on humanity than all their domestic policies put together. This is why much the rest of the world follows American politics and the current presidential race gets almost as much coverage as a local election in some places. It is also why hearing Sarah Palin speak on the matter leaves me cold.
*And environmental policy, at least the aspects that respect no national boundaries.
More of the interview can be found here and here ("America [is] a beacon of light in the world").